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The sentences given below, when properly sequenced, would yield a coherent paragraph. Decide on the proper sequencing of the order of the sentences and key in the sequence of the numbers as your answer.

  1. Scientists have for the first time managed to edit genes in a human embryo to repair a genetic mutation, fuelling hopes that such procedures may one day be available outside laboratory conditions.
  2. The cardiac disease causes sudden death in otherwise healthy young athletes and affects about one in 500 people overall.
  3. Correcting the mutation in the gene would not only ensure that the child is healthy but also prevents transmission of the mutation to future generations.
  4. It is caused by a mutation in a particular gene and a child will suffer from the condition even if it inherits only one copy of the mutated gene.
  5. In results announced in Nature this week, scientists fixed a mutation that thickens the heart muscle, a condition called hypertrophic cardiomyopathy.

Entered answer:

Solution

✅ Correct Answer: 15243

Step 1: Find the opening sentence -> Sentence 1 introduces the main topic about scientists editing genes in human embryos

Step 2: Look for specific details -> Sentence 5 gives the exact example of what was done (hypertrophic cardiomyopathy)

Step 3: Follow the explanation chain -> Sentences 2 and 4 explain what this disease does and how it's caused

Step 4: Find the conclusion -> Sentence 3 wraps up with the benefits of fixing the mutation


From passage: "Scientists have for the first time managed to edit genes in a human embryo" and "In results announced in Nature this week, scientists fixed a mutation that thickens the heart muscle"

Thought Process:

General statement (1) -> Specific example (5) -> Disease effects (2) -> Disease cause (4) -> Solution benefits (3)

This creates a smooth flow: Introduction -> Example -> Problem description -> Problem cause -> Solution outcome


Since no options are provided, the correct sequence is 15243 based on this logical progression:

• 1 opens with the breakthrough announcement

• 5 specifies what exactly was done

• 2 describes the disease's impact

• 4 explains the genetic cause

• 3 concludes with the benefits of the solution

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